Cell Therapy & Gene Therapy Equipment worked example

Cell Therapy Capacity Gap at 65% expected equipment uptime and availability: a worked example

This worked example runs the cell therapy capacity gap numbers for a tougher week than the baseline: 65% expected equipment uptime and availability instead of the typical 90%. Estimate the gap between required production demand and usable cell therapy or gene therapy equipment capacity.

The inputs for this scenario

  • Qualified released units per equipment cycle: 6 released units / cycle (held at the documented default)
  • Available equipment cycles in the period: 80 cycles / period (held at the documented default)
  • Expected equipment uptime / availability: 65 % (the input this scenario stresses; the baseline uses 90)
  • Expected lot release yield: 86 % (held at the documented default)

Working through the calculation

  • The calculation starts from the formula this tool documents: Gross scheduled capacity = qualified output per cycle × available equipment cycles.
  • Usable released capacity works out to 268 released units at these inputs, and this is the headline figure for the scenario.
  • Gross scheduled capacity works out to 480 released units at these inputs.
  • Capacity lost to equipment downtime works out to 168 released units at these inputs.
  • Capacity lost to unreleased output works out to 43.68 released units at these inputs.

How this compares with the baseline

  • Against the tool's baseline example, where expected equipment uptime and availability sits at 90% and the headline result is 372 released units, this scenario comes in 27.78% below the baseline at 268 released units.
  • Use it for capacity planning, demand commitments, and constraint analysis on a specific bioreactor, perfusion, or fill platform. A result at this level usually justifies acting on the stressed input before touching anything else, because every other figure in the table is downstream of it.

Results at a glance

  • Usable released capacity: 268 released units (headline result)
  • Gross scheduled capacity: 480 released units
  • Capacity lost to equipment downtime: 168 released units
  • Capacity lost to unreleased output: 43.68 released units

Run it with your numbers

  • To rerun this with your own numbers, open the live Cell Therapy Capacity Gap calculator, set expected equipment uptime and availability to your actual value, and adjust the remaining inputs to match your operation.

Last reviewed 2026-05-12.