Cell Therapy & Gene Therapy Equipment worked example

Process Hold Time at 23% transfer, setup, and documentation allowance: a worked example

Push transfer, setup, and documentation allowance up to 23% and the picture changes. This example computes every intermediate figure at that operating point. a manufacturing or MSAT team is checking whether queued work fits the allowed process hold-time window

The inputs for this scenario

  • Queued batches, samples, or containers: 24 items (unchanged)
  • Clearing rate for the next GMP step: 0.8 items / min (unchanged)
  • Transfer, setup, and documentation allowance: 23 % (raised for this scenario; the documented default is 20)

Working through the calculation

  • Applying the documented formula (Base queue clearing time = queued items รท clearing rate for the next GMP step) to the inputs above produces each figure below.
  • At this operating point the engine returns 36.9 min for adjusted process hold time, the number this scenario is built around.
  • At this operating point the engine returns 30 min for base queue clearing time.
  • At this operating point the engine returns 23 % for hold-time allowance applied.
  • At this operating point the engine returns 0.8 items / min for gmp step clearing rate.

How this compares with the baseline

  • Against the tool's baseline example, where transfer, setup, and documentation allowance sits at 20% and the headline result is 36 min, this scenario comes in 2.5% above the baseline at 36.9 min.
  • It computes base queue-clearing time as queued items divided by the step clearing rate, then inflates it by a transfer, setup, and documentation allowance. The value of this scenario is the size of the gap it exposes: that gap, priced out over a year, is the budget you can justify spending to close it.

Results at a glance

  • Adjusted process hold time: 36.9 min (headline result)
  • Base queue clearing time: 30 min
  • Hold-time allowance applied: 23 %
  • GMP step clearing rate: 0.8 items / min

Run it with your numbers

  • Every input above is editable in the live Process Hold Time calculator, which recalculates instantly and can be shared with the inputs intact.

Last reviewed 2026-05-12.