Pharmaceutical, Biotech & GMP Manufacturing worked example

Tablet Compression Throughput at 65% accepted tablet yield: a worked example

Suppose accepted tablet yield falls to 65%. This page works the full calculation at that level so you can see exactly which result moves and by how much. Estimate effective tablet compression throughput from tablets compressed, run hours, and accepted tablet yield.

The inputs for this scenario

  • Tablets compressed: 1,200 tablets (held at the documented default)
  • Compression run time: 8 hr (held at the documented default)
  • Accepted tablet yield: 65 % (the input this scenario stresses; the baseline uses 90)

Working through the calculation

  • The calculation starts from the formula this tool documents: Gross throughput = Tablets compressed รท Compression run time.
  • Effective throughput works out to 97.5 units/hr at these inputs, and this is the headline figure for the scenario.
  • Raw throughput works out to 150 units/hr at these inputs.
  • Efficiency works out to 65 % at these inputs.
  • Runtime works out to 8 hr at these inputs.

How this compares with the baseline

  • Against the tool's baseline example, where accepted tablet yield sits at 90% and the headline result is 135 units/hr, this scenario comes in 27.78% below the baseline at 97.5 units/hr.
  • It computes effective good-tablet throughput per hour by dividing tablets compressed by run time and scaling by accepted yield. When the numbers land here, the stressed input is the lever to work; the walkthrough above shows exactly how much each output recovers as it climbs back toward the baseline.

Results at a glance

  • Effective throughput: 97.5 units/hr (headline result)
  • Raw throughput: 150 units/hr
  • Efficiency: 65 %
  • Runtime: 8 hr

Run it with your numbers

  • To rerun this with your own numbers, open the live Tablet Compression Throughput calculator, set accepted tablet yield to your actual value, and adjust the remaining inputs to match your operation.

Last reviewed 2026-05-12.